RULE OUT LYSOSOMAL ACID LIPASE DEFICIENCY (LAL D)

LAL D is a life-threatening, progressive disease that could be hidden among your patients, as it is commonly confused with heterozygous familial hypercholesterolemia (HeFH), nonalcoholic fatty liver disease (NAFLD)/nonalcoholic steatohepatitis (NASH), and metabolic syndrome.1-3

LEARN HOW TO DIAGNOSE LAL D

References:  1. Bernstein DL, et al. Cholesteryl ester storage disease: review of the findings in 135 reported patients with an underdiagnosed disease. J Hepatol. 2013;58:1230-43. doi:10.1016/j.jhep.2013.02.014.  2. Hülkova H, et al. Distinctive histopathological features that support a diagnosis of cholesterol ester storage disease in liver biopsy specimens. Histopathology. 2012;60:1107-13. doi:10.1111/j.1365-2559.2011.04164.x.  3. Reiner Ž, et al. Lysosomal acid lipase deficiency—an under-recognized cause of dyslipidaemia and liver dysfunction. Atherosclerosis. 2014;235:21-30. doi:10.1016/j.atherosclerosis.2014.04.003.